G Protein-Coupled Receptors - Zhao Xinfeng
G Protein-Coupled Receptors - Zhao Xinfeng
- Immobilization and Applications in Drug Discovery
AutorzyZhao Xinfeng
EAN: 9789819900770
Marka
Symbol
297HJP03527KS
Rok wydania
2023
Strony
104
Oprawa
Miekka
Format
15.6x23.4cm
Język
angielski

Bez ryzyka
14 dni na łatwy zwrot

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Marka
Symbol
297HJP03527KS
Kod producenta
9789819900770
Rok wydania
2023
Strony
104
Oprawa
Miekka
Format
15.6x23.4cm
Język
angielski
Autorzy
Zhao Xinfeng

This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the "post-structural biology" era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other related field, as well as teachers of relevant majors in colleges and universities.
EAN: 9789819900770
EAN: 9789819900770
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