Mesenchymal-Epithelial Interactions in Neural Development - Wolff Joachim R.
Mesenchymal-Epithelial Interactions in Neural Development - Wolff Joachim R.
EAN: 9783642718397
Marka
Symbol
040HHS03527KS
Rok wydania
2011
Strony
450
Oprawa
Miekka
Format
17.0x24.4cm
Redakcja
Wolff Joachim R.
Język
angielski

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Marka
Symbol
040HHS03527KS
Kod producenta
9783642718397
Rok wydania
2011
Strony
450
Oprawa
Miekka
Format
17.0x24.4cm
Redakcja
Wolff Joachim R.
Język
angielski

This book is based on the NATO Advanced Research Workshop on "Mesenchymal-Epithelial Interactions in Neural Development" which was held in Berlin during March 1986. The idea that it may be the time for this workshop
arose from a discussion among the organizers who met at a conference in Innsbruck. During the twenties, Spemann demonstrated that, in vertebrates, the formation of neuroepithelium depends on the induction by specific
mesodermal derivatives. This was about the first time that mesenchymal-epithelial interactions had been recognized as an important mechanism in the development of an epithelial organ. Since then two things had become clear: 1)
The identity and role of molecules, elaborated at mesenchymal-neuroepithelial interfaces had been partially elucidated in spinal cord and peripheral nerve ontogeny but, until recently, had been ignored in studies on the
development of the brain. 2) In many-non-neural epithelia, the surrounding mesenchyme regulates such fundamental developmental steps as, for example, cell proliferation, morphogenesis and cell differentia tion, and there is
no reason to exclude similar influences and interactions from brain development. It seemed to us that the importance and implications of many of these findings had not been appreciated by many developmental neurobiologists and
that an attempt should be made to initiate discussions and exchange of ideas among different groups of scientists involved in extracellular matrix (ECM) research. This turned out to be a formidable task because of the great
diversity of disciplines contributing findings to this active field.
EAN: 9783642718397
EAN: 9783642718397
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