Glutamine Metabolism in Mammalian Tissues - Häussinger D.
Glutamine Metabolism in Mammalian Tissues - Häussinger D.
EAN: 9783642697562
Marka
Symbol
056HGF03527KS
Rok wydania
2011
Strony
316
Oprawa
Miekka
Format
17.0x24.4cm
Redakcja
Häussinger D.
Język
angielski

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Marka
Symbol
056HGF03527KS
Kod producenta
9783642697562
Rok wydania
2011
Strony
316
Oprawa
Miekka
Format
17.0x24.4cm
Redakcja
Häussinger D.
Język
angielski

Glutamine is a key aminoacid for the synthesis of numerous biologic ally important compounds in mammalian cells and is a carrier form of ammonia. The advance in knowledge on the metabolic significance of this amino
acid is presented in in-depth treatments by experts in this active research field. This includes the enzymology of glutamine synthe tase and glutaminase activities in different mammalian organs, notably liver, kidney and
brain; properties of glutamine transport across bio logical membranes; role of glutamine metabolism in the liver, with emphasis on the recent discovery of intercellular heterogeneity with respect to enzyme distribution and
its functional consequences for ammonia/urea metabolism and pH regulation; renal and intestinal glutamine metabolism; cerebral glutamine/ glutamate interrelationships; skeletal muscle; role of glutamine in cell culture; and
finally the clinical aspects, including the new outlook of glutamine antagonists in cancer therapy as well as the role of glutamine in hepatic coma and encephalo pathy. Some, but not all, of the contributors to this work
attended the 48th Conference of the Gesellschaft fur Biologische Chemie on glutamine metabolism held in Gottingen, W. Germany, in September 1983. This conference was supported by the Stiftung Volkswagenwerk, Dr. H. Falk
Foundation, Freiburg, and the J. Pfrimmer Co. , Erlangen. The abstracts of the contributions to the conference were published in Hoppe-Seyler's Z. Physiol. Chem. 364,1237-125,6,1983, and this book is not intended as the
proceedings of that meeting.
EAN: 9783642697562
EAN: 9783642697562
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